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These include: Severe injection site reactions with spreading redness, warmth, or swelling Rash or hives suggesting an allergic response Anaphylaxis (facial swelling, breathing difficulty, collapse) Skin changes associated with signs of pancreatitis (severe abdominal pain radiating to the back) Symptoms suggestive of thyroid tumours (neck mass, difficulty swallowing, persistent hoarseness, breathing difficulties) Rapidly spreading cellulitis at injection site or blistering/mucosal rash Persistent skin problems that significantly impact quality of life or psychological wellbeing Referral to a dermatologist may be appropriate for severe nodulocystic acne, acne with scarring or risk of scarring, failure of 12 weeks of appropriate therapy, significant psychological impact, or clinical features of hyperandrogenism (e.g., hirsutism, irregular menses)

Individual responses vary significantly, and not all patients experience measurable anti-inflammatory benefits

Most patients should aim for sufficient fluid intake throughout the day rather than consumed in large amounts at once

Wegovys prior authorization criteria vary by plan